Females become infertile as the stored sperm's oxygen radicals increase

Females become infertile as the stored sperm's oxygen radicals increase

Reduced metabolic rate and oxygen radicals production in stored insect sperm.

Females of internally fertilizing species can significantly extend sperm lifespan and functionality during sperm storage. The mechanisms for such delayed cellular senescence remain unknown. Here, we apply current hypotheses of cellular senescence developed for diploid cells to sperm cells, and empirically test opposing predictions on the relationship between sperm metabolic rate and oxygen radi...

Oxygen radicals and signaling.

Recent evidence suggests that reactive oxygen species, such as superoxide anions and hydrogen peroxide, function as intracellular second messengers. This review will discuss the progress in understanding the intracellular pathways leading from ligand stimulation to the generation of oxidants, as well as some of the increasing number of cellular processes that appear to be subject to redox regul...

Highly stable dendritic trityl radicals as oxygen and pH probe.

Novel dendritic trityl radicals (DTR1 and DTR2) with a TAM radical core, PAMAM branching and carboxylate exterior surface exhibit high stability towards oxidoreductants as evidenced by their electrochemical and EPR properties, offering potential application as dual oxygen and pH probe.

Oxygen radicals, oxygen toxicity and the life of microorganisms.

The electronic structure of dioxygen in the ground state dictates that its reduction occur most easily by a univalent pathway which involves the dangerously reactive intermediates 02, H202 and OH. The oxygenation of earth’s biosphere 3.5 x 10~ years ago provided both opportunity and threat. The opportunity to exploit oxygen for energy-yielding and biosynthetically useful oxidations has been sei...